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AMLGHAGDM details
Primary information
ID antitb_1440,
Name25809751
N-Terminal modificationA2-TB10.4
C-Terminal ModificationAMLGHAGDM
Chemical ModificationFree
Linear/CyclicFree
LengthNone
ChiralityLinear
Nature9
SourceL
SpeciesProtein derived
StrainMTB derived protein TB10.4
Inhibition ConcentrationMycobacterium tuberculosis
In Vitro/ In vivoMycobacterium tuberculosis Rv
Sequence2104
CytotoxicityNA
In vivo ModelNA
Lethal DoseNA
Immune ResponceNA
Mechanism of ActionNA
TargetIL7Rα expression reduced and CD107a expression also decreased among CD8+ T cell after post TB treatment
Combination TherapyDrug treatement of TB with antiTB drug found to decrease the frequency of MTB Antigen CD8+ T-cell, so evaluation of these antigenic peptide after TB treatment serve as a valuable marker for the evaluation of TB therapy.
Other activitiesCD8+ T-cell
PMIDNA
Year of PublicationNA
Tertiary Structure
(Technique)
Not Predicted),